Tuesday, January 25, 2011

Ameliox - Botox-Like Alternative

Wrinkles are the consequence of the weakening of the connective tissue. Weakening happens because of stiffening and consequent degradation of the structural components, the collagen fibres. A chemical reaction between free sugars and collagen, called glycation, is the cause for stiffening. Glycation is nowadays considered as one of the main reasons why living organisms are subjected to aging.

The active substances in Ameliox, Carnosine and Silymarin have been shown to effectively inhibit glycation. Carnosine reacts very quickly with free sugars and prevents them to attack collagen fibres. Silymarin, a polyphenolic substance isolated from milk thistle, is a highly effective antioxidant. Because oxidation is an essential reaction step in the glycation process, Silymarin is also an inhibitor of glycation.

Ameliox - cosmetic anti-aging ingredient to stop stiffening of collagen fibres

Ameliox is a powerful combination of two actives to stop stiffening of collagen fibres, a major reason for formation of wrinkles and lines. Ameliox contains Carnosine and the milk thistle compound silymarin (INCI: Silybum Marianum Fruit Extract). Carnosine, a naturally-occurring dipeptide in the human body, has anti-aging properties by inhibition of the detrimental glycation reaction. The antioxidant Silymarin is another powerful glycation inhibitor.
Ameliox is proven to decrease wrinkle depth

Mibelle AG Biochemistry tested an emulsion with 2% Ameliox in a clinical study with 20 women. The test product was applied twice daily for four weeks on the inner side of the forearm and on the forehead and the area with crow's feet. Ameliox improved significantly hydration, firmness and smoothness of the forearm skin (data not shown) and clearly reduced wrinkle depth on the forehead and around the eyes (crow's feet).